rgc marker rbpms polyclonal antibody (Proteintech)
Structured Review

Rgc Marker Rbpms Polyclonal Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 48 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rgc marker rbpms polyclonal antibody/product/Proteintech
Average 95 stars, based on 48 article reviews
Images
1) Product Images from "Reln-Dab1 pathway mitigates retinal ganglion cell apoptosis in retinal ischemia-reperfusion injury"
Article Title: Reln-Dab1 pathway mitigates retinal ganglion cell apoptosis in retinal ischemia-reperfusion injury
Journal: Cell Death & Disease
doi: 10.1038/s41419-025-07742-6
Figure Legend Snippet: A Schematic representation of the experimental design (Created with BioRender.com). B Histopathological examination of retinal tissue stained with H&E showed that the inner retinal thickness of mice was significantly reduced after I/R injury. This I/R-induced inner retinal thinning was significantly improved in mice treated with exogenous Reelin protein. Scale bar: 80 μm. C Quantification of inner retinal thickness ( n = 6). D Representative OCT images of retinal tissue demonstrate changes after I/R injury. E Quantification of total retinal thickness ( n = 6). F Representative fluorescent staining of retinal patches after I/R injury showed the RBPMS-positive RGCs (orange) distribution. Supplementation with Reelin protein exerted a significant protective effect on I/R-induced RGC injury. Scale bars: 100 μm or 1 mm. G Number of RBPMS-positive RGCs ( n = 4). H Representative oscillatory potential waveforms of visual function were assessed via FERG 7 days after I/R injury. I Quantification of the magnitude of a and b waves ( n = 6). Data are represented as means ± SD. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001.
Techniques Used: Staining
Figure Legend Snippet: A Schematic representation of the experimental design (Created with BioRender.com). B Frozen slides showing retinal infection 3 weeks after intravitreal injection of AAV. EGFP carried by AAV was expressed in nearly all the layers of the retina. Scale bar: 40 μm. C The expression level of Reelin protein in the inner retinal layer was assessed by the intensity of the fluorescence signals ( n = 6). D The mRNA expression of the Reln gene ( n = 6). E Histopathological examination of retinal tissue via H&E staining showed that the inner retinal thickness in AAV- shReln mice was further reduced after I/R injury. The damage to I/R-induced RGCs was further aggravated in AAV- shReln mice. Scale bar: 80 μm. F Quantification of inner retinal thickness ( n = 6). G Representative OCT images of retinal tissue changes after I/R injury. H Quantification of total retinal thickness ( n = 6). I Representative fluorescent staining of retinal patches after I/R injury showed the distribution of RBPMS-positive RGCs (orange). Scale bars: 100 μm or 1 mm. J Number of RBPMS-positive RGCs ( n = 4). K Representative oscillatory potential waveforms of visual function were assessed by FERG after I/R injury. L Quantification of the magnitude of a and b waves ( n = 6). Data are represented as means ± SD. * P < 0.05, ** P < 0.01, *** P < 0.001.
Techniques Used: Infection, Injection, Expressing, Fluorescence, Staining